Cardiovascular risk assessment

CARDIOVASCULAR RISK ASSESSMENT The risk of developing heart, stroke or blood vessel disease (cardiovascular disease) in the next five years (10 and 30 years for the US calculator). Online calculators: Australia: www.cvdcheck.org.au UK: https://qrisk.org/three/ USA: https://professional.heart.org/en/guidelines-and-statements/prevent-risk-calculator/prevent-calculator [+] yes, [-] no, [?] unknown NOTE: Clinically determined high risk (calculation NOT necessary): [-] Moderate-severe chronic kidney disease: [-] sustained eGFR <45 mL/min/1.73 m^2). [-] persistent uACR >25 mg/mmol (men) or >35 mg/mmol (women). [-] Familial hypercholesterolaemia. Parameters: (^Optional, not required for calculators) Sex (M/F): Age (years): Systolic blood pressure (mmHg): Smoking history: [-] Never smoked [-] Previously smoked [-] Currently smokes [-] Being treated for hypertension [-] Taking aspirin therapy^ [-] LVH on ECG^ [-] History of AF^ [-] Diabetes mellitus If yes^: Years since Diagnosis/es: HbA1c: uACR (mg/mmol): eGFR (mL/min/1.73 m^2): Weight (kg): Height (m): Insulin use in the last 6 months (Yes/No): Lipid studies: Total cholesterol (mmol/L): LDL cholesterol (mmol/L): HDL cholesterol (mmol/L): Ratio of total cholesterol to HDL cholesterol: Triglyceride^ (mmol/L): ABSOLUTE CARDIOVASCULAR RISK %: Risk interpretation: [-] Low <5% [-] Medium 5 to <10% [-] High 10%+ Risk enhancing factors: [-] Family history of premature ASCVD (males, age <55 years; females, age <65 years). [-] Primary hypercholesterolemia (LDL cholesterol 4.1-4.8 mmol/L [160-189 mg/dL]; non-HDL cholesterol 4.9-5.6 mmol/L [190-219 mg/dL]). [-] Metabolic syndrome (increased waist circumference [by ethnically appropriate cutpoints], elevated triglycerides [>1.7 mmol/L, non-fasting {150 mg/dL}], elevated blood pressure, elevated glucose, and low HDL cholesterol [<1.03 mmol/L {<40 mg/dL} in males; 1.29 mmol/L {<50 mg/dL} in females] are factors; a tally of 3 makes the diagnosis). [-] Chronic kidney disease (eGFR 15 to 59 mL/min/1.73 m2 with or without albuminuria; not treated with dialysis or kidney transplantation). [-] Chronic inflammatory conditions, such as psoriasis, RA, lupus, or HIV/AIDS. [-] History of premature menopause (before age 40 years) OR history of pregnancy-associated conditions that increase later ASCVD risk, such as preeclampsia. [-] High-risk race/ethnicity (eg, South Asian ancestry, Australian ATSI). [-] Lipids or biomarkers associated with increased ASCVD risk (IF MEASURED): [-] Persistently elevated* primary hypertriglyceridemia (≥1.98 mmol/L [≥175 mg/dL], non-fasting). [-] Elevated high-sensitivity C-reactive protein (≥2 mg/L). [-] Elevated Lp(a): A relative indication for its measurement is family history of premature ASCVD. An Lp(a) ≥50 mg/dL or ≥125 nmol/L constitutes a risk-enhancing factor, especially at higher levels of Lp(a). [-] Elevated apoB (≥2.53 umol/L [≥130 mg/dL]): A relative indication for its measurement would be triglyceride ≥2.26 mmol/L (≥200 mg/dL). [-] ABI (ankle-brachial SBP index) <0.9. Coronary artery calcium score (CAC) Consider if 40+ years of age and: [-] Moderate CV risk. [-] There are risk-enhancing factors where risk might be underestimated.

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Related items

• Body mass analysis
• Cardiovascular system
• Health Targets for Adults

External links

Online Risk Calculators

Cardiovascular risk calculators

• Australia [-] Australian absolute cardiovascular disease risk calculator [-] National Vascular Disease Prevention Alliance (NVDPA)
• UK [-] QRISK 3 calculator
• USA [-] American Heart Association PREVENT™ Risk Calculator (Includes 10 and 30-year risk calculations)

Familial Hypercholesterolaemia Calculators

• Dutch Lipid Clinical Network Score (DLCNS) Online Calculator [-] Australian Atherosclerosis Society